Toxicological Studies on the Sinai Plant Urginea maritima (Scilla) in Wistar Albino Rats

The varied toxicity of Urginea maritima (a plant that grows in north Sinai) on Wistar albino rats was investigated. Twenty-four weighing 100±20 gm. were divided into 4 groups, the first group, which included six male rats, and second female given di-methyl sulfoxide orally for 45 consecutive days regarded as control groups. third group who received 36 mg/kg B.W (1/20 LD50 from alcoholic extract maritima) succession. fourth made up a daily dose 26 extract) successive days. Serum samples taken biochemical study after end experiment, sciatic nerve, heart, brain tissues also histopathological analysis. findings demonstrated significant changes exposed animals' serum levels calcium (Ca++), sodium (Na+), potassium (K+) ions. While K+ dramatically increased, Ca++ Na+ significantly dropped. Lactic acid dehydrogenase (LDH) creatine kinase (CK-MB) activities increased. In addition, pathological alterations brain, nerve discovered when compared to